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Non-Hodgkin's Lymphoma
Last updated October 2004
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Putting It All Together

Here is a summary of the important facts and information related to Non-Hodgkin's Lymphoma.

  • Lymphoma is a cancer  A disease in which any of the body's cells begin to divide out of control, causing a tumor to form or too many of these cells to spread throughout the body. of the lymphatic system  The tissues and organs that produce, store, and carry white blood cells that fight infection and other diseases. This system includes the bone marrow, spleen, thymus, and lymph nodes and a network of vessels that carry lymph and white blood cells into all the tissues of the body. , which carries lymph  The almost colorless fluid that travels through the lymphatic system and carries cells that help fight infection and disease. fluid and white blood cells  The cells of the immune system that fight infection, attack foreign substances or cells, and sometimes kill cancer cells. throughout the body. White blood cells fight infection.

  • There are two main types of lymphoma: Hodgkin's disease, and non-Hodgkin's lymphoma.

  • A non-Hodgkin's lymphoma diagnosis used to be very bad news. Now medical treatments can cure many cases. New, even better treatments are also being developed.

  • The first sign of lymphoma is often a painless lump or swollen gland in the neck, abdomen  The center part of the body that contains the stomach, intestines, liver, gallbladder, and other organs. , underarm, or groin  The area in the body where the thigh meets the abdomen. area.

  • Many other things can cause swollen glands. Swollen glands due to infection are usually fairly soft and somewhat tender or painful, while cancerous nodes are usually firm, rubbery and painless.

  • Your doctor and oncologist  A doctor who specializes in diagnosing and treating cancer. will do a number of tests to define the lymphoma's grade  A measure of how quickly a tumor is growing and stage  A measure of how far a cancer has spread throughout the body. Stages range from Stage I, which is a localized tumor that has not spread, to Stage IV, in which the cancer has spread to parts of the body far away from the original tumor. Stage I cancers have a better outlook than do Stage IV cancers.. Then they can design the best possible treatment approach.

  • Grade refers to how quickly the tumor  An abnormal mass of tissue that occurs when cells divide out of control. Tumors may be either benign (not cancerous) or malignant (cancerous). Benign tumors do not spread throughout the body and when they are removed they do not grow back. Malignant, or cancerous, tumors may do both. is growing. High-grade, aggressive lymphomas are fast-growing and can be deadly in a short time, but can often be cured with proper treatment. Low-grade, indolent lymphomas are slow-growing, but tend to recur  To occur again, to come back. Even when lymphoma appears cured, it may recur. after treatment.

  • Stage refers to how far the cancer has spread throughout the body. The lower the stage, the less the lymphoma has spread and the better the outlook.

  • The two forms of treatment that are used most often for lymphoma are chemotherapy  Treatment with anti-cancer drugs. (drugs) and radiation therapy  A form of treatment that uses high-energy radiation from x-rays, neutrons, and other sources to kill cancer cells and shrink tumors. . Promising new biological therapies are also being developed.

  • Chemotherapy and radiation therapy can be difficult both physically and emotionally. Try to remember that your therapy will not last forever. There are many support groups and sources of information that can help you through the difficulty of your diagnosis and treatment.

  • There are things you can do to make your therapy go as smoothly as possible. Talking to your doctor, trying to follow a healthy lifestyle, and sticking to recommendations and follow-up care will help your medical team help you.

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